The Reds have an Easter Monday road-trip south to take on the Hatters.
With very little time to prepare for this one, after Friday night's 1-1 draw with Reading at Oakwell, supporters will no doubt be hoping for a perfect end to their bank holiday weekend as their side look to stay strong in their pursuit of a playoff place.
In what was one of the most entertaining of drawn games just two days ago, Barnsley had to fight back for a point against a Reading outfit just behind them in the race for a top six finish.
Skipper, Alex Mowatt slotted home a second half penalty to cancel out Ovi Ejaria's well-taken Royals opener in the first 45.
Whilst the Reds were handed a let-off when Lucas Joao contrived to miss an open goal, they'll feel they did enough on the night to take all three points in a game they dominated, but for the woodwork and another decision by the officials to disallow a Barnsley goal.
Reds striker Daryl Dike was once again adjudged to have fouled the goalkeeper from a corner kick, as Michał Helik bundled home what he thought was the winning goal.
That is the third instance of Barnsley scoring goals this season at Oakwell that have been dubiously chalked off. It was only in the previous game where again Dike was supposedly fouling the Sheffield Wednesday 'keeper, despite being nowhere near him as he failed to hold a cross that was swept home by Cauley Woodrow.
And the Reds' number 9 himself had a strike ruled out in a 2-2 draw with Cardiff City earlier this year, where he himself was the one fouled.
Along with the handball shouts ignored/unseen by officials that have also cost Barnsley this term, and the wrongful dismissal of Mowatt a few weeks ago, it must mean the Reds are due a lot of favourable decisions, if indeed the old 'levelling out' theory rings true. We aren't holding our breath.
Next up then is the long trip south to Bedfordshire and Kenilworth Road to take on a Luton Town side who've had quite the season themselves.
After joining the Reds in securing safety on the final day last year, the Hatters - under Nathan Jones - have also kicked on magnificently this season and sit comfortably in mid-table ahead of this one.
They're 13th at present on 50 points and have won two of their last three games. They were defeated away at Wayne Rooney's Derby County on Good Friday.
The Hatters came out on top in the reverse fixture right at the start of the season, at Oakwell. A cracking James Collins strike on 71 minutes clinched the points for Luton.
Town are unbeaten in four, in this fixture. But they haven't beaten the Reds in the league at Kenilworth Road for 28 years.
Amongst the Hatters squad remain a number of former Barnsley players, such as Martin Cranie, Matty Pearson, James Bree, George Moncur, Luke Berry, Jordan Clark and Ryan Tunnicliffe.
We have live coverage via iFollow Barnsley of this Easter Monday clash, as Matt Bailey is joined once again on the mic by ex-Red Wayne Goodison.