Burnley, managed by former Watford boss Sean Dyche, currently sit in 11th position in the npower Championship, 10 points ahead of the Reds in the table having played one match more.
The Clarets have picked up seven wins and five draws from their 17 home league games so far this season, scoring 23 goals and conceding 17 - their last home victory a 1-0 win over Crystal Palace.
Flitcroft's troops will be looking to take confidence from second-half dominance against Bolton at the weekend, despite on the wrong end of a 3-2 scoreline, and take it into tonight's clash with the Clarets. The last victory for Barnsley over Burnley on their own patch was on Boxing Day 2008.
Boxing Day 2008: Jamie Cureton celebrates his goal with Jamal Campbell-Ryce and the Reds faithful
It was on that Boxing Day clash that the Reds last registered a goal at Turf Moor, with Chris McCann deflecting in a Campbell-Ryce effort which saw Simon Davey's side earn the festive three points 2-1.
Despite proving a solid, well-oiled outfit under Sean Dyche - it's difficult to look beyond striker Charlie Austin as the Clarets' main threat. There was reported interest from Everton in January as Austin continued to hit the net with ease for Burnley, but the hitman has stuck with the Lancashire side and so far has an incredible 25 goals to his name.
The forward will be hoping to notch another goal against the Reds, having headed home in the reverse fixture at Oakwell which ended in a 1-1 draw - Marcus Tudgay replaying for the Reds.
Going to the match?
Can't make it to Turf Moor?
Tickets will remain on sale from the Oakwell Box Office until 12 noon on Tuesday 5th March.